Abstract

A 65-year-old woman was hospitalized for evaluation of unstable angina. For several years, she had experienced occasional episodes of mild chest discomfort on exertion. Three days before admission, she had begun to have more severe discomfort on mild exertion, with several episodes occurring while she was at rest. The ECG (Figure A, page 28) showed left bundle branch block, which had been present for several years.In the hospital, during treatment with aspirin and heparin, she was clinically stable, with no further chest discomfort. Creatine kinase levels were normal. A coronary arteriogram showed areas of severe narrowing in the left anterior descending and diagonal branches; the stenoses were treated by balloon angioplasty. Twelve hours later, the patient experienced sudden severe chest pain, dyspnea, and a fall in blood pressure, from 135/80 mm Hg to 100/65 mm Hg.The ECG recorded at that time is shown below.

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