Abstract

We are able to detect subclinical post-irradiation changes to the heart with left atrial late gadolinium enhanced magnetic resonance imaging (LGE-MRI).

Highlights

  • There are over 11 million cancer survivors, yet many long-term cancer survivors experience lasting changes including cardiac functional and anatomical abnormalities following external beam radiation and chemotherapy

  • A total of 20 patients were enrolled in this study; 10 patients who had survived 9.2 ± 25 years after thoracic external beam radiation for lymphoma and 10 control patients recruited from the University colonoscopy center

  • The extent of late gadolinium enhancement was calculated as a relative percent of total left atrial wall using a threshold-based algorithm based on pixel intensity distribution

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Summary

Open Access

Left atrial late gadolinium enhancement following external beam radiation for lymphoma: a potential model for exploring radiation-related heart disease. Summary We are able to detect subclinical post-irradiation changes to the heart with left atrial late gadolinium enhanced magnetic resonance imaging (LGE-MRI)

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