Abstract
We studied 10 patients with Alzheimer disease by measuring EEG compressed spectral analysis and the P<sub>300</sub> latency and topography before and after 2 weeks of lecithin therapy. There was a significant positive correlation between the degree of dementia measured by the Blessed Dementia Scale and the amount of EEG delta activity. The P<sub>300</sub> latency was related to the ability to detect the rare tones in the P<sub>300</sub> paradigm. Lecithin therapy increased mean plasma choline levels but did not affect EEG power or the P<sub>300</sub> latency or topography.
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