Abstract
AbstractThe performance of a bioreactor composed of two chemostats in series can be affected significantly by the split of feed into two, one for each chemostat, for reactions following Monod kinetics. Under certain operating conditions, split of feed can be greatly beneficial to the reactor performance.Optimization of performance is discussed; a general criterion is presented, applicable to either the maximization of overall conversion for a given total residence time or the minimization of total residence time for a given overall conversion. The maximization of overall conversion has also been studied with respect to the feed‐split ratio. The dimensionless Michaelis‐Menten constant is a very important parameter in the selection of optimal operating conditions.
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