Le récepteur minéralocorticoïde altère, in vivo, la fonction du pancréas endocrine et de l’adipocyte

Abstract

The abutment of adjacent fields has been facilitated through the use of asymmetric collimators. Conceptually, the abutment yields a perfectly uniform dose distribution across the junction, provided the asymmetric jaw is set precisely at the beam central axis. However, the asymmetric jaw has an associated tolerance, which can cause the abutment to be misaligned. This study examined the dose distribution at the junction of nonperfectly abutted fields. The abutment of fields was carried out using an asymmetric collimation of 5 × 10 cm, with an asymmetric jaw positioned at the beam central axis. A film was initially exposed using this field with the collimator set at 90°. The collimator was then rotated 180° and the same film was exposed for the second time to create the field abutment. Positioning the asymmetric jaw with respect to the beam central axis set the amount of gap and overlap between the abutted fields. The dose distribution was measured for asymmetric jaw positioning of −2, −1, 0, +1, and +2 mm from the beam central axis. In addition, the dose distribution was also computed mathematically by summing the 2 dose profiles with defined gap or overlap. A field mismatch of ±1 mm would result in a dose nonuniformity of 17%, and a ±2 mm mismatch would produce a 35% dose nonuniformity.