Abstract
To investigate the prevalence of human papillomaviruses (HPV) in cancers located at different sites in patients from west Algerian and collected between 2010and 2014. Extracted DNA from archival formaldehyde-fixed and paraffin-embedded tissues was provided from 39anogenital cancers, 10head and neck cancers and 36skin cancers. The viral DNA was detected using the INNO-LiPA HPV Genotyping Extra(®) kit. The prevalence of HPV was 100% in cervical cancers, 40% in vaginal cancers, 17% in vulvar cancers, 33% in anal cancers, 0% in tonsil and larynx cancers and 6.4% in skin squamous cell carcinoma. In cervical cancers, the most prevalent genotypes were HPV16 (52%) and HPV18 (12%) as single infection. The overall results agree partially with literature. Extensive research is necessary to promote HPV vaccine to reduce in particular the burden of cervical cancer in Algeria.
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