LDA-Mediated Selective Addition Reaction of Vinylidenecyclopropanes with Aldehydes, Ketones, and Enones: Facile Synthesis of Vinylcyclopropenes, Allenols, and 1,3-Enynes

Abstract

Highly selective addition reaction of vinylidenecyclopropanes 1 was realized by treatment with LDA in THF and quenching with aldehydes, ketones, and enones. A number of vinylcyclopropenes, allenols, and 1,3-enynes were obtained selectively in moderate to good yields depending on the nature of different electrophiles.