Abstract
We present the cases of two prepubertal girls with a clinical picture characterized by systemic and oropharyngeal symptoms a few days before the appearance of vulvar ulcers.We aim to highlight the importance of performing a differential diagnosis among distinct sexually-transmitted diseases and of excluding the possibility of sexual abuse in these patients. The development of acute vulvar ulcer is rare and this entity is often underdiagnosed because of its low incidence and difficult diagnosis. Although this process is self-limiting, early treatment is important to minimize symptoms. Diagnosis is based on clinical findings and the exclusion of other causes of genital ulcers. Treatment is based on the administration of anti-inflammatory and/or antipyretic agents. Local topical anesthetics can also be used. Most patients can be treated as outpatients. If urination is impossible due to pain, hospital admission may be required for catheterization.
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