Abstract
Objective: This study was aimed at examining the role of modifiable risk factors to association between hypertension and coronary heart disease in the central general hospital Dr. M. Djamil Padang, West Sumatra, Indonesia. Design and Method: A hospital-based matched case control study was conducted from December 2014 to April 2015. We studied 171 samples with 1:2 ratio between the case and the control. Samples were collected using simple random sampling by matching the age and sex. Data were analyzed using McNemar's test and conditional logistic regression was performed for multivariate modeling. Results: The result showed that the variables associated with coronary heart disease are hypertension had OR = 16.04 (95%CI 5.705–45.12), obesities had OR = 2.53 (95%CI 1.321–4.844), and hyperuricemia had OR 2.41 (95%CI 1.292–4.516. Multivariate modeling showed that hyperuricemia had a confounder between associated hypertension and coronary heart disease. Multivariate modeling showed hypertension had the highest risk to coronary heart disease. The effect of hypertension on coronary heart disease after controlling for obesity and hyperuricemia variable is equal to OR = 15.86. Conclusions: Hypertension is a strong associated with coronary heart disease. People are expected to manage their blood pressure to decrease the risk of coronary heart disease.
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