Abstract
Checkpoint inhibitor (CPI) combinations improve clinical outcomes for patients (pts) with advanced RCC. BEMPEG is a pegylated IL-2 prodrug, designed with the intent to preferentially bind to IL-2Rβγ. PIVOT-09 is a Phase III, randomized trial of BEMPEG + NIVO vs VEGF-targeted tyrosine kinase inhibitor (TKI) of investigator’s choice for 1L RCC (NCT03729245).
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