Abstract
Ultraviolet A (UVA) radiation is one of the main causes of skin photoaging. UVA is the principal component of solar UV radiation and penetrates deeper into the skin than UVB and UVC. Salicylic acid (SA) is widely used in skin rejuvenation as a superficial chemical exfoliator and has shown a potential anti-photoaging property. However, the role and mechanism of SA in UVA-induced photoaging have not been fully addressed. In the present study, we established a UVA-induced photoaging mouse model by 10J/cm2/day UVA exposure for 10 days, SA was applied 30 min before UVA radiation.
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