Abstract

Immune checkpoint inhibitors(ICIs) have been associated with the development of multiple cutaneous and/or extracutaneous immune-related adverse events(cirAEs/irAEs). Given the prevalence and morphologic diversity of cirAEs, multiple distinct toxicities are particularly common in the skin, but these patterns remain poorly characterized. We sought to examine associations among multiple cirAE status, cirAE features, and irAE risk in patients receiving ICIs. In this retrospective cohort study, we screened patients initiating ICI therapy at MGH (1/1/16-6/29/21) who developed cirAEs and abstracted clinical history.

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