Abstract
Purpose: For years, concern has persisted that hydroquinone exposure in humans may be associated with increased risk of cancer but proving this has been elusive. The purpose of this study is to use the TriNetX database to quantify the cancer risk associated with hydroquinone use in humans. Methods: We used the TriNetX platform to create 2 cohorts of patients, both without any prior diagnosis of skin cancer. One cohort had received prior hydroquinone exposure which was determined by medication code 5509 in the TriNetX system, while the other was prohibited from having such exposure.
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