Abstract
A functional network of blood vessels is essential for organ growth and homeostasis. While we possess substantial knowledge of the cellular mechanisms that dictate skin development and homeostasis, much is still not known concerning the cellular and tissue morphogenic events that dictate cutaneous vascular remodeling. To shed light on these fundamental biological processes, we performed longitudinal imaging in the skin of live mice using 2-photon microscopy. We systematically evaluated the same capillaries and endothelial cells (ECs) in neonatal mice, tracking their behaviors as the skin plexus expanded and reached adulthood.
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