Abstract
Mast cells significantly increase and activate in psoriasis lesions and are involved in psoriatic inflammation. Neuroblast differentiation-associated protein (AHNAK) mainly express in skin, esophagus, kidney and other organs, which participates in the differentiation of neurons, the formation of cytoskeletal structure muscular regeneration, and the calcium homeostasis process. Whether AHNAK is involved in mast cell activation is unclear, and the mechanisms of AHNAK-induced skin inflammation also need investigation.
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