Abstract
Epidermal growth factor (EGF) ligands play a key role in cellular proliferation and cancer progression via activation of the EGF receptor (EGFR). However, EGFR inhibitors (EGFRIs) frequently induce a rash in patients that is associated with improved cancer survival, suggesting immunomodulatory properties that may be therapeutically beneficial. Human keratinocytes (HaCaT) were treated with IFN-γ (a potent pro-inflammatory cytokine), EGF, both, or neither (control) and differentially expressed genes (DEGs) were analyzed using RNA-seq and gene-set enrichment analyses.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Paper version not known
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
