Abstract

Alopecia is a common chief complaint and is challenging to treat. Exosomes, extracellular vesicles formed by sequential invagination of membranes between intracellular components, are involved in cell communication, homeostasis, and differentiation, and play a key role in hair morphogenesis and regeneration with potential for alopecia treatment use. To summarize the current body of knowledge surrounding exosomes and identify areas for research, a literature review was conducted using keywords including “exosome,” “alopecia,” and “hair loss” on PubMed, EMBASE, and Google Scholar databases to assess exosome use, postulated underlying mechanisms, and clinical applications.

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