Abstract
DNA sensors achieve qualitative or quantitative detection of analyte by recognizing DNA probes that bind to the target analyte and convert them into various signals. Layered double hydroxides (LDHs) have been widely used for the construction of DNA sensors due to their large specific surface area, good electrocatalytic activity and anion adsorption, and structural ease of adjustability, which in turn enable the analyte of a wide range of substances, such as DNA, RNA, and pharmaceuticals. In recent years, LDHs-based sensors have attracted widespread attention of researchers and have been used to detect various analytes. Therefore, this paper reviews the preparation and influencing factors of LDHs as well as the characteristics and types of DNA sensors, with a focus on summarizing the application of LDHs-based DNA sensors in the field of analytical detection.
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