Abstract

The therapeutic value of Eugenia jambolana Lam. commonly known as ‘Jamun’ has been recognized in different system of traditional medication for the treatment of different diseases and ailments. It contains several phytoconstituents belonging to category of alkaloids, glucosides, flavonoides and volatile oils. It has been reported as digestive, astringent to the bowels, anthelmintic, sore throat, bronchitis, asthma, thirst, biliousness, dysentery, blood purifier, ulcers and diabetes. There are few reports available on clinical uses of Eugenia jambolana in diabetes that have shown promising results. In south India ayurvedic practitioners were using the leaf buds of Eugenia jambolana to induce laxative effect and to clean up the intestinal contents before starting any medication. The result showed that of E. jambolana stimulates the contractile action of frog and mice through an acetylcholine-like mechanism and effectively stimulates gastrointestinal motility in mice and frogs. In this paper we have discussed the laxative effect of Eugenia jambolana leaf bud extract which was never reported scientifically.

Highlights

  • Traditional or indigenous drugs used by different ethnic groups of the world for the treatment of diseases have special significance of having been tested on long time scale

  • The result showed that of E. jambolana stimulates the contractile action of frog and mice through an acetylcholine-like mechanism and effectively stimulates gastrointestinal motility in mice and frogs

  • In case of the albino mice the castor oil was very effective with respect to time taken to exert laxative effect

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Summary

Introduction

Traditional or indigenous drugs used by different ethnic groups of the world for the treatment of diseases have special significance of having been tested on long time scale. They are relatively safe, available and affordable to masses. Eugenia jambolana Lam belonging to the family Myrtaceae is a large evergreen tree up to 30 m high It is widely distributed through out India, and known as Jamun. According to Ayurveda, its bark is acrid, sweet, digestive, and astringent to the bowels, anthelmintic and in good for sore throat, bronchitis, asthma, thirst, biliousness, dysentery, blood impurities and to cure ulcers [1-8]. The present study was carried out to provide pharmacological evidence for the folkore medicinal consideration of leaf bud crude extract as laxative

Results
Spasmogenic Effect in Isolated Frog Ileum
Discussion
Materials and methods
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