Lauromacrogol injection and autologous concentrated growth factors gel membrane for venous leg ulcers

Abstract

Objective To observe the efficacy of Lauromacrogol injection combined with autologous concentrated growth factors gel membrane in the treatment of venous leg ulcers, and to find a treatment method with small trauma and high curative effect. Methods The clinical data of 46 patients with varicose ulcer wounds treated at Tangxia Hospital from January, 2013 to October, 2018 were summarized and analyzed. The 25 patients in the treatment group were treated with high saphenous vein ligation, Lauromacrogol injection for calf varicose veins, and autologous concentrated growth factors gel membrane. The 21 patients in the control group underwent high saphenous vein ligation, Lauromacrogol injection for calf varicose veins, and conventional dressing for ulcer wounds. The wound areas before the treatment and the wound healing times after treatment of the two groups were compared. Results Before the treatment, the wound area of the treatment group was (5.97±2.46) cm2, and that of the control group (5.47±3.01) cm2 (P>0.05). After the treatment, the wound healing time was (12.76±3.42) d in the treatment group, and was (28.19±7.37) d in the control group (t=9.352, P=0.000). Conclusion Lauromacrogol injection combined with autologous concentrated growth factors can promote the healing of venous leg ulcers, which is an effective means for the treatment of venous leg ulcers. Key words: Varicose Ulcer; concentrated growth factors; Lauromacrogol; Wound healing; Sclerotherapy