Abstract
AimsTo explore the effect of latitude on incidence of multiple sclerosis (MS) in Scotland. MethodsMS case data (2010–2015) was ascertained from the Scottish Multiple Sclerosis Register. Patient's postcode at diagnosis was linked to the Scottish Index of Multiple Deprivation (SIMD). Geographical data from SIMD was converted into latitude and longitude and patients were grouped by latitude band. A linear regression analysis was then performed. MS Cumulative Incidence was compared to population density calculated from SIMD. ResultsLatitude was associated with MS Incidence rate. Using a linear regression analysis (r2 = 0.22, p = 0.03), the data predicted an increase in the average MS Incidence of 1.31 cases/100,000 person years per increase in degree latitude. MS Cumulative Incidence rates rise with increasing northern latitude up until 59° north. ConclusionsWe found an increasing incidence of MS with latitude without any relationship to population in Scotland. The reasons for this are likely to be multifactorial.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
