Abstract
The SARS-CoV-2 pandemic led to an unprecedented demand for PPE and generated a small-scale industry making personalised face coverings. Concerns had been raised about the use of natural rubber latex (NRL) as an elastomeric material, with its health risks. We have investigated the levels of four NRL allergens and total protein in elastomeric ear-straps in manufactured face coverings and the material sold for their production, and a number of imported N95/KN95 PPE masks. None of the samples identified whether NRL was involved or not. NRL allergens levels in manufactured masks were low or not detectable; 3/10 of the N95/KN95 masks showed levels above the limit of detection, probably reflecting low-level cross-contamination during manufacture. Three batches of material sold for “the manufacture of ear straps for face coverings” had significant but variable levels of allergen (250–2526 ng/g of material). Historically, extractable protein measurements have been used as an indicator of possible NRL proteins. This study showed significant levels of apparent protein in sample extracts without measurable NRL allergens or confirmation by electrophoresis. Therefore, the immunochemical measurement of NRL allergens remains key to rule out elastomeric material with the potential to cause latex-related health problems.
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