Abstract
In 1969, Pierre Flor-Henry reported that when psychosis developed in association with a left hemisphere seizure focus, it tended to be schizophrenia-like; whereas a seizure focus in the right hemisphere was more likely associated with an affective psychosis [ [1] Flor-Henry P. Psychosis and temporal lobe epilepsy: a controlled investigation. Epilepsia. 1969; 10: 363-395 Crossref PubMed Scopus (579) Google Scholar ]. Soon thereafter, Flor-Henry published in 1976 the paper reprinted here, “Lateralized Temporal-Limbic Dysfunction and Psychopathology,” in the Annals of the New York Academy of Sciences [ [2] Flor-Henry P. Lateralized temporal-limbic dysfunction and psychopathology. Ann. NY Acad. Sci. 1976; 280: 777-795 Crossref PubMed Scopus (370) Google Scholar ]. In it, he extended those earlier observations of psychosis in epilepsy to mental illness independent of epilepsy, and in so doing, he triggered a still ongoing international inquiry into issues of laterality and psychopathology.
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