Abstract

Solitary fibrous tumors (SFTs) are rare tumors thought to be of mesenchymal origin. Even though intracranial, especially intraventricular, SFTs are rare, this diagnosis should be considered in the differential for intraventricular lesions. Here, report the case of a female in her 60s who underwent a non-contrast-enhanced magnetic resonance imaging scan of the brain for new-onset memory issues and headache which revealed a well-circumscribed intraventricular lesion in the right lateral ventricle with vasogenic edema, trapping of the temporal horn, and subfalcine herniation. She was admitted and started on dexamethasone prior to surgical treatment of the tumor. A right-sided superior parietal lobule approach was utilized to reach and resect the lesion. Histopathology was consistent with World Health Organization grade I SFT. Only 10 other cases of lateral ventricular SFTs have been reported in the literature. Intraventricular SFT is a rare diagnosis, and, as such, the literature on this topic mostly consists of case reports. Although the lesion is benign, metastases have been reported, and thus, gross total resection remains the standard of care. This case adds to the paucity of SFTs reported in the literature.

Highlights

  • Solitary fibrous tumor (SFT) was first pathologically characterized in 1931 by Klemperer and Rabin [1]

  • SFT is of mesenchymal origin, and common differential considerations include meningioma, schwannoma, fibrosarcoma, and, when intraventricular, choroid plexus papilloma [4]

  • We describe a rare case of SFT arising in the lateral ventricles

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Summary

Introduction

Solitary fibrous tumor (SFT) was first pathologically characterized in 1931 by Klemperer and Rabin [1]. Half of intraventricular solitary fibrous tumors (ISFTs) originate in the lateral ventricles. A 64-year-old female presented to the internal medicine clinic for two weeks of lightheadedness upon standing and memory issues regarding work she had performed for decades How to cite this article Nguyen A, Shan Y, Lyon K, et al (March 12, 2022) Lateral Ventricle Solitary Fibrous Tumor: A Case Report and Review of the Literature. The option of surgical resection via a superior parietal lobule (SPL) approach was considered due to its ability to spare the sensorimotor cortex and optic radiations. This approach was discussed with the patient, and she provided informed consent to proceed. SFT: solitary fibrous tumor; STAT-6: signal transducer and activator of transcription 6

Discussion
60 F 40 M 63 M 75 F 44 F 55 F Not specified – two patients
Conclusions
Disclosures
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