Abstract
This study aimed to test whether or not a digital workflow for GBR with particulate bone substitutes and injectable platelet-rich fibrin improved the thickness of the hard tissue compared to the conventional workflow. 26 patients in need of lateral bone augmentation were enrolled. GBR with particulate bone substitutes and injectable platelet-rich fibrin was performed in all patients. Patients were divided into two groups: control (conventional workflow; n = 14) and test (digital workflow; n = 12). CBCT scans were performed before surgery, immediately after wound closure, and 6 months post-surgery, and the labial thickness of the hard tissue (LT) was assessed at 0–5 mm apical to the implant shoulder (LT0–LT5) at each time point. A total of 26 patients were included in this study. After wound closure, the test group showed significantly greater thickness in LT0–LT2 than the control group (LT0: test: 4.31 ± 0.73 mm, control: 2.99 ± 1.02 mm; LT1: test: 4.55 ± 0.69 mm, control: 3.60 ± 0.96 mm; LT2: test: 4.76 ± 0.54 mm, control: 4.05 ± 1.01 mm; p < 0.05). At 6 months, significant differences in LT0–LT1 were detected between the groups (LT0: test: 1.88 ± 0.57 mm, control: 1.08 ± 0.60 mm; LT1: test: 2.36 ± 0.66 mm, control: 1.69 ± 0.58 mm; p < 0.05). Within the limitations of this study, the use of digital workflow in GBR with particulate bone substitutes and i-PRF exerted a positive effect on the labial thickness of hard tissue in the coronal portion of the implant after wound closure and at 6 months.
Highlights
Alveolar bone remodeling and resorption processes following tooth removal induce gradual changes in both soft and hard tissue dimensions [1]
We introduced a novel guided bone regeneration (GBR) procedure using digital surgical templates for shaping the injectable platelet-rich fibrin (i-PRF) block based on the concept of prosthetic-guided regeneration, and it was confirmed that this procedure contributes to achieving an appropriate bone graft contour after wound closure [21]
Twenty-six patients were included in this study (12 in the test group and 14 in the control group)
Summary
Alveolar bone remodeling and resorption processes following tooth removal induce gradual changes in both soft and hard tissue dimensions [1]. Driven bone regeneration procedures are required to reconstruct ridge contours for implant placement in the prosthetically ideal position and achieve optimized esthetic and functional outcomes [2]. Resorbable collagen membranes in combination with particulate bone substitutes are widely used in GBR procedures with long-term clinical success, as they have the 4.0/). The major drawback of particulate bone substitutes and collagen membranes is their poor mechanical properties [11]. Compressive forces generated during the wound closure and healing period can lead to the collapse of collagen membranes and the apical displacement of particulate bone substitutes, thereby impairing space maintenance and new bone formation [12,13]
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