Late-onset, Eruptive Syringoma in an Elderly Man: Correlation with Carbamazepine

Abstract

Syringomas are benign neoplasms of the eccrine sweat gland ducts that commonly appear around the eyelids in women. Clinically, they manifest as small, skin-coloured or slightly pigmented papules. Syringoma is classified into four clinical types: localized; familial; Down’s syn-drome associated; and generalized, which encompasses multiple and eruptive syringomas (1). Furthermore, clear cell syringoma, which is characterized by histological proliferation of clear cells, has been reported to be asso-ciated with diabetes mellitus (2). Eruptive syringoma is a rare variant and usually appears before or during puberty (3). The lesions occur in large numbers and in successive crops on the neck, chest, abdomen, maxillae and genitalia. We describe here a case of late-onset eruptive syringoma in a 69-year-old man and discuss its possible association with an anti-epileptic drug. CASE REpoRTA 69-year-old man was referred to our department for the evaluation of skin lesions, which he had first noti-ced at the age of approximately 60 years. The lesions had first appeared on his abdomen, and3 years ago the