Abstract
Diabetes mellitus is considered one of the main threats to human health in the 21st century. Diabetes is a metabolic disorder or a chronic condition where the sugar levels in blood are high. Diabetes is associated with long-term complications that affect almost every part of the body and often leads to blindness, heart and blood vessel disease, stroke, kidney failure, amputations, and nerve damage. Also it is associated with significantly accelerated rates of several debilitating microvascular complications such as nephropathy, retinopathy, and neuropathy, and macrovascular complications such as atherosclerosis and stroke. In the present article it has been discussed about the resistance of insulin and its consequences in diabetic patients. Insulin resistance results in various disorders. Metabolic syndrome is predicted to become a major public health problem in many developed, as well as developing countries.
Highlights
Diabetes mellitus is considered one of the main threats to human health in the 21st century
The prevalence of diabetes is increasing, where there are, as estimated by the World Health Organization (WHO), around 70 million people suffering from diabetes mellitus [1].Changes in human behaviour and lifestyle over the last century have resulted in a dramatic increase in the incidence of diabetes worldwide [2]
The type 1 diabetes mellitus (T1DM) or type 2 diabetes mellitus (T2DM) is a multifactorial autoimmune disease [4], which susceptibility is determined by a combination of genetic and environmental factors
Summary
Diabetes mellitus is considered one of the main threats to human health in the 21st century. Diabetes is a metabolic disorder or a chronic condition where the sugar levels in blood are high. It is defined as chronic disorders [3] of carbohydrate metabolism due to the lack of insulin result in the hyperglycemia and glycosuria. As diabetes is a metabolic disorder, people with diabetes are in a risk of other complications associated. The metabolism is affected there by causes various complications. Diabetes is associated with long-term complications that affect almost every part of the body and often leads to blindness, heart and blood vessel disease, stroke, kidney failure, amputations, and nerve damage. Diabetes is associated with significantly accelerated rates of several debilitating microvascular complications such as nephropathy, retinopathy, and neuropathy, and macrovascular complications such as atherosclerosis and stroke
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