Abstract

Objective: To evaluate the effectiveness of topical 0.4% ketorolac tromethamine usage with contact lenses following laser-assisted in situ keratomileusis (LASIK) surgery, for post-operative pain reduction. Material and Methods: Two hundred and ninety two eyes of 146 patients who underwent LASIK surgery under topical anesthesia were included in the study. Contact lenses soaked in a 0.4% solution of ketorolac tromethamine were applied to 148 eyes of 74 patients who had undergone LASIK surgery for refractive errors (Group 1). Contact lenses with no medication were applied to 144 eyes of 72 patients who had undergone LASIK surgery for refractive errors (Group 2). Pain scores were recorded in both groups every hour from hour 1 to hour 5, postoperatively. Results: There were no significant differences between the two groups with regard to age or sex (p>0.05). No significant difference was found between the two groups in respect of either preoperative or postoperative mean uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), and intraocular pressure values (p>0.05). The mean postoperative UCVA was significantly better than the mean preoperative UCVA in both groups (p<0.05). Pain scores for Group 1 patients at postoperative hours 2, 3, and 4 were significantly lower than for patients in Group 2 (p<0.001, p<0.001 and p=0.023, respectively). Topical ketorolac tromethamine did not negatively affect wound healing, corneal flap, or ocular surface in any patient. Conclusion: Topical ketorolac tromethamine application with contact lenses following LASIK surgery decreases pain and discomfort effectively.

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