Abstract
In laser speckle imaging methods, speckle correlation coefficient analysis (SCCA) shows great potential in blood flow monitoring because of its high sensitivity to slow flows than laser speckle contrast imaging (LSCI). But the published SCCA usually depends on short exposure times and high frame rates to preserve the autocorrelation. Differently, in this paper we use SCCA at normal exposure time (20 ms) to evaluate the performance of skin optical clearing (SOC) and demonstrate that SCCA with long exposure time also significantly improves the ability to image large range of flow speeds over LSCI.
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