Abstract
Current study involves laser-induced gold nanoparticles (GNPs) for breast cancer therapy. GNPs as a therapeutic agent using nanophotolysis approach are discussed. Coulomb explosion of GNPs is studied numerically using MATLAB. Our findings show that [Formula: see text] ions are generated for short pulse laser interaction of 8 ns and laser irradiation of 2 J/cm2 penetrates in the tumor depth of 3.30 cm. Cluster size of 98 nm produced [Formula: see text] nanobullets that target the breast tumor. Short pulse laser of 2.27 ns generates maximum shock front velocity of [Formula: see text] cm/s. Shock front of 20–146 [Formula: see text]m is produced for effectively damaging the breast cancer tissues. A total of 825 cells are damaged by [Formula: see text] ions. Current results are matched with the literature and are in good correlation. Hence, we conclude that laser-irradiated GNPs using nanophotolysis approach are useful for targeted therapy of breast tumor.
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