Abstract
Here, the fluorescence properties of some plant-based drug samples are characterized using a coherent excitation source at 405 nm. The laser-induced fluorescence (LIF) spectroscopy is examined to analyze opium and hashish. In order to improve traditional fluorescence methods for better analysis of optically dense materials, we have proposed five characteristic parameters based on solvent densitometry assay as the fingerprints of drugs of interest. The signal emissions are recorded in terms of various drug concentrations, such that the best fitting over experimental data determines the fluorescence extinction (α) and self-quenching (k) coefficients according to the modified Beer-Lambert formalism. The typical α value is determined to be 0.30 and 0.15 mL/(cm∙mg) for opium and hashish, respectively. Similarly, typical k is obtained 0.390 and 1.25 mL/(cm∙mg), respectively. Furthermore, the concentration at max fluorescence intensity (Cp) is determined for opium and hashish to be 1.8 and 1.3 mg/mL, respectively. Results reveal that opium and hashish benefit their own characteristic fluorescence parameters to discriminate those illicit substances promptly using the present method.
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More From: Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
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