Abstract
This study was designed to assess the quantitative features of the skin protecting mechanism of axon reflexes by monitoring stimulus related changes in skin blood flow using laser Doppler flowmetry. Skin vasodilatation induced by trains of brief transcutaneous electrical pulses (0.5 ms, 150 V) was strictly related in magnitude to the number of pulses (trains of 1-32). This vascular response was reduced by 95% when the skin had been pretreated by painting it for two days with a 1% alcoholic solution of capsaicin. The sensitivity of vascular responses to activation of afferent C-fibers indicates a role of this mechanism in the protection of the skin against noxious events.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.