Abstract

In this research work, we studied µTAS (µ total analysis system) method to measure the deformability of red blood cells .We took the sample of RBCs(red blood cells) in a micro fluidic based chamber, then allowed low intensity laser of infra red region, mostly at wavelength 1064 nm, to fall on the sample. This generated a cavitation bubble in the fluid because of evaporation mechanism involved. We tightly hold the slides containing blood sample so that the displacement of RBCs (red blood cells) stay confined in the viewing area of the microscope. Firstly the deformation due to expansion of cavitation bubble was sighted and then came the restoring of shape of RBCs (red blood cells) which was possible due to a focused and pulsed laser. The RBCs restored their shape after some time and was viewed with the help of a video recorded by a high- speed camera. In this way the plastic character and elastic properties of RBCs (red blood cells) was measured.

Highlights

  • LASER technology has been under research for decades and because of its low intensity therapy utilized in medical applications

  • Since history to the prevailing time, there are variety of ways have been used to talk about the mechanical properties of red blood cells (RBCs) G

  • To avoid all the obstacles, we demonstrate a more generalized and easy method to treat many RBCs at a time inside a chamber with the help of a single laser induced cavitation bubble Pedro A

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Summary

Introduction

LASER technology has been under research for decades and because of its low intensity therapy utilized in medical applications. Since history to the prevailing time, there are variety of ways have been used to talk about the mechanical properties of RBCs (red blood cells) G. To avoid all the obstacles, we demonstrate a more generalized and easy method to treat many RBCs (red blood cells) at a time inside a chamber with the help of a single laser induced cavitation bubble Pedro A.

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