Laser assisted zona hatching: factors affecting success rates

Abstract

ObjectiveTo analyze the impact of assisted zona hatching.DesignRetrospective analysis.Materials and MethodsPatients with repeated IVF/ET failure or patients > 40 years.The study population was divided into two subgroups Group A: included failed cycles, Group B: included cycles that achieved clinical pregnancy.ResultsThe study included 416 women (582 cycles), 498 cycles (361 patients) failed to achieve clinical pregnancy while in 84 cycles (82 patients) clinical pregnancy was achieved. The mean age of group B was found to be younger than that of group A: 35 ± 5.8 vs. 37.9 ± 5.7 (p<0.0001). There was a negative relation between women age and pregnancy rates, higher pregnancy rates were obtained in younger women (p= 0.0039). Pregnancy rates were significantly lower when only one embryo was transferred per cycle (p=0.0456). There was no relation between number of retrieved and fertilized oocytes in each AZH treatment cycle and pregnancy rates (p= 0.775 & 0.379 respectively). There was no relation between number of previous treatments or failures and pregnancy rates (p=0.428 & 0.224 respectively).ConclusionWoman age is a highly considerable factor affecting the success rates of AZH treatments. Women who underwent plenty of treatments, or have a history of lots of failures, are still good candidates for AZH treatments but, there is a tendency for lower pregnancy rates, the more consecutive failures the patient underwent before the current AZH treatment. ObjectiveTo analyze the impact of assisted zona hatching. To analyze the impact of assisted zona hatching. DesignRetrospective analysis. Retrospective analysis. Materials and MethodsPatients with repeated IVF/ET failure or patients > 40 years.The study population was divided into two subgroups Group A: included failed cycles, Group B: included cycles that achieved clinical pregnancy. Patients with repeated IVF/ET failure or patients > 40 years.The study population was divided into two subgroups Group A: included failed cycles, Group B: included cycles that achieved clinical pregnancy. ResultsThe study included 416 women (582 cycles), 498 cycles (361 patients) failed to achieve clinical pregnancy while in 84 cycles (82 patients) clinical pregnancy was achieved. The mean age of group B was found to be younger than that of group A: 35 ± 5.8 vs. 37.9 ± 5.7 (p<0.0001). There was a negative relation between women age and pregnancy rates, higher pregnancy rates were obtained in younger women (p= 0.0039). Pregnancy rates were significantly lower when only one embryo was transferred per cycle (p=0.0456). There was no relation between number of retrieved and fertilized oocytes in each AZH treatment cycle and pregnancy rates (p= 0.775 & 0.379 respectively). There was no relation between number of previous treatments or failures and pregnancy rates (p=0.428 & 0.224 respectively). The study included 416 women (582 cycles), 498 cycles (361 patients) failed to achieve clinical pregnancy while in 84 cycles (82 patients) clinical pregnancy was achieved. The mean age of group B was found to be younger than that of group A: 35 ± 5.8 vs. 37.9 ± 5.7 (p<0.0001). There was a negative relation between women age and pregnancy rates, higher pregnancy rates were obtained in younger women (p= 0.0039). Pregnancy rates were significantly lower when only one embryo was transferred per cycle (p=0.0456). There was no relation between number of retrieved and fertilized oocytes in each AZH treatment cycle and pregnancy rates (p= 0.775 & 0.379 respectively). There was no relation between number of previous treatments or failures and pregnancy rates (p=0.428 & 0.224 respectively). ConclusionWoman age is a highly considerable factor affecting the success rates of AZH treatments. Women who underwent plenty of treatments, or have a history of lots of failures, are still good candidates for AZH treatments but, there is a tendency for lower pregnancy rates, the more consecutive failures the patient underwent before the current AZH treatment. Woman age is a highly considerable factor affecting the success rates of AZH treatments. Women who underwent plenty of treatments, or have a history of lots of failures, are still good candidates for AZH treatments but, there is a tendency for lower pregnancy rates, the more consecutive failures the patient underwent before the current AZH treatment.