Abstract
Otolaryngologists and gastroenterologists seem to differ in their definitions and management of laryngopharyngeal reflux (LPR). In this review article, the author suggests a multidisciplinary approach to LPR diagnosis. Based on the latest findings, the author proposes an algorithm to facilitate the assessment and management of LPR.
Highlights
Laryngopharyngeal reflux (LPR), referred to as extra-esophageal reflux, supra-esophageal reflux, or silent reflux, refers to a condition in which gastroduodenal content rises up the esophagus and affects the throat, the laryngopharynx [1,2,3,4,5,6]
Gastroenterologists have questioned whether reflux contributes to LPR-related symptoms in patients with no gastroesophageal reflux disease (GERD)-associated manifestations [11]
upper gastrointestinal endoscopy (UGE) can detect signs associated with GERD, such as mucosal injury, esophagitis, and Barrett esophagus as well as other complications and malignancies; UGE has proven less useful in detecting LPR than in identifying GERD [12,18]
Summary
Laryngopharyngeal reflux (LPR), referred to as extra-esophageal reflux, supra-esophageal reflux, or silent reflux, refers to a condition in which gastroduodenal content rises up the esophagus and affects the throat, the laryngopharynx [1,2,3,4,5,6]. Otolaryngologists and gastroenterologists differ in their definitions and management of LPR [4,10,11,12]. Otolaryngologists treat LPR as a relatively new clinical entity, whereas gastroenterologists treat LPR as a rare extra-esophageal manifestation of gastroesophageal reflux disease (GERD) [10,13]. Gastroenterologists have questioned whether reflux contributes to LPR-related symptoms in patients with no GERD-associated manifestations [11]. Otolaryngologists have pointed out that LPR is a multifactorial syndrome that involves gaseous and/or nonacid refluxate [14,15]. Based on the latest findings in LPR research, we propose an algorithm aimed at facilitating the assessment and management of LPR
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