Abstract

Renal allograft recipients are at greater risk of developing tuberculosis than the general population. A woman with a kidney transplant was admitted to our emergency department with high temperature, dysphonia, odynophagia, and asthenia. The final diagnosis was laryngeal tuberculosis. Multidisciplinary collaboration enabled accurate diagnosis and successful treatment. Laryngeal tuberculosis should be considered in renal allograft recipients with hoarseness. A more rapid diagnosis of tuberculosis in renal transplant recipients is desirable when the site involved, such as the larynx, exhibits specific manifestations and the patient exhibits specific symptoms. In these cases, prognosis is excellent, and with adequate treatment a complete recovery is often achieved.

Highlights

  • Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis [1]

  • We present the case of a renal transplant recipient who developed laryngeal TB

  • A 38-year-old woman with chronic renal failure caused by chronic diabetes mellitus from the age of 9 was admitted to the Emergency Department of the Sapienza University Hospital, Rome, Italy, in December 2018 with high temperature, dysphonia, odynophagia, general discomfort, and severe asthenia

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Summary

INTRODUCTION

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis [1]. Geographically, most TB cases in 2018 were in Southeast Asia (44%), Africa (24%), and Western Pacific nations (18%); smaller numbers of cases have occurred in Eastern Mediterranean nations (8%), the Americas (3%), and Europe (3%) [1]. A 38-year-old woman with chronic renal failure caused by chronic diabetes mellitus from the age of 9 was admitted to the Emergency Department of the Sapienza University Hospital, Rome, Italy, in December 2018 with high temperature, dysphonia, odynophagia, general discomfort, and severe asthenia. She reported having undergone a thoracotomy with right-sided pneumectomy at the age of 16 for previous pulmonary aspergillosis, and renal transplantation in 2015 at the age of 35 and subsequent treatment with steroids, mycophenolate mofetil, and tacrolimus. The patient is not isolated and undergoes regular follow-up visits with clinical examinations and CT scans every 2 months

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