Abstract
Mosquitoes are the most important medical insect, that transmits diseases, such as dengue fever and malaria. The biological effects of new Organophosphorus Schiff base compounds (2-Furalidenediphenylphosphate-1-phenylsemicarbazide OPSL1) and 2-methoxybenzalidenediphenylphosphate-1-phenylsemicarbazide OPSL2) against the mosquito larvae of Aedes aegypti was evaluated at different concentrations using WHO standard susceptibility test with some modifications. A laboratory bioassay was conducted to assess the larvicidal activity under controlled laboratory conditions, late 3rd or early 4th instar larvae were exposed to various concentrations – ranging from 150 ppm to 1200 ppm of the tested compounds. Mortalities were observed to increase with the increase in concentrations. The results showed that OPSL2 revealed significantly high activity against Ae. aegypti with (LC50 = 600.6 ppm) compared to the OPSL1, with LC50 = 642.9 ppm respectively. Further investigations would be required to evaluate the new active Organophosphorus compounds responsible for larvicidal efficacy in the future.
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