Abstract
We have analyzed DNA restriction fragment length polymorphism to determine whether the mutation responsible for Laron Type Dwarfism (LTD) is linked to the human growth hormone (hGH) gene. An hGH haplotype represents the combination of presence or absence of variable restriction sites for Bgl II, Hinc II and Msp I at 5 locations in a single 55 kb hGH gene cluster. We studied 3 Israeli families with LTD. Different haplotypes are indicated by capital letters A-D:
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