Abstract

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Highlights

  • Lipodystrophy syndromes, a clinically diverse group of conditions with selective deficiency of adipose tissue as a central feature, are classified as inherited or acquired, with further sub-classification based on aetiology and clinical features.[1]

  • Known as Barraquer-Simons syndrome, is a rare condition first described in 1885 by Mitchell.[2]. It is characterised by progressive accumulation of surplus subcutaneous fat in the hips and lower limbs, contrasted with a deficiency of fat in the upper body, as well as metabolic complications of hypertriglyceridaemia and insulin resistance.[3]

  • Medical management and largevolume liposuction are effective in improving the metabolic profile of patients without lipodystrophy, as well as cosmesis and quality of life.[5,7,8]

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Summary

Introduction

Lipodystrophy syndromes, a clinically diverse group of conditions with selective deficiency of adipose tissue as a central feature, are classified as inherited or acquired, with further sub-classification based on aetiology and clinical features.[1]. 1 Department of Plastic Surgery St Vincent’s Hospital Darlinghurst, New South Wales AUSTRALIA 2 Department of Diabetes and Endocrinology St Vincent’s Hospital Darlinghurst, New South Wales AUSTRALIA 4 Diabetes and Metabolism Group Garvan Institute of Medical Research Darlinghurst, New South Wales AUSTRALIA

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