Abstract
Decompressive craniectomy is widely used for treating patients with traumatic brain injury (TBI). Usually patients have dura mater defect due to surgery or injury itself. The defective area may left open or repaired by artificial dura substitutes. A variety of artificial dura substitutes have been used for this purpose.
Highlights
Traumatic brain injury (TBI) is a complex injury with a broad spectrum of symptoms and disabilities, and it is the leading cause of death for individuals in our society between the ages of 1 and 45 (Rutland‐Brown, Langlois, Thomas, & Xi, 2006)
Patients with severe brain injury, based upon neurologic status defined by the Glasgow coma scale (GCS), usually need emergent surgical intervention, and decompressive craniectomy is a common procedure to release intracranial pressure (ICP) and open up brain cavity for further surgical treatment (Compagnone et al, 2005)
387 patients with severe TBI were included in this study, 192 patients were treated with standard decompressive craniectomy without dura repair (Control group), and 195 patients were treated with decompressive craniectomy followed artificial dura material repair (ADM group)
Summary
Traumatic brain injury (TBI) is a complex injury with a broad spectrum of symptoms and disabilities, and it is the leading cause of death for individuals in our society between the ages of 1 and 45 (Rutland‐Brown, Langlois, Thomas, & Xi, 2006). Many patients may have significant dura mater defect due to TBI itself or by surgery. The defective dura area may be left open without repair or sealed with artificial dura substitutes (Huang, Lee, Chen, & Wang, 2011; Mundinger et al, 2016; Wang et al, 2015; Zhang, Yang, Jiang, & Zeng, 2010). Both procedures have been widely used and have distinctive advantages and disadvantages, for instance, patients without dura repair may have increased risk of CSF leakage and infection, while have better decompressive effect. There lacks of large clinical studies to compare clinical outcomes of both procedures in TBI patients
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