Abstract
Large plexiform neurofibroma of the lower extremity
Highlights
Plexiform neurofibroma is an uncommon variant of neurofibroma, a benign tumor of peripheral nerves (WHO grade I) [1], arising from a proliferation of all neural elements
Plexiform neurofibromas are essentially pathognomonic of neurofibromatosis type 1 (NF1)
Unlike small sporadic localized neurofibromas and diffuse cutaneous neurofibromas, these tumors are at a significant risk of eventual malignant [2]
Summary
Plexiform neurofibroma is an uncommon variant of neurofibroma, a benign tumor of peripheral nerves (WHO grade I) [1], arising from a proliferation of all neural elements.
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