Abstract

Ossifying fibroma (OF) is a rare, benign fibro-osseous tumor, which occurs at various locations in the maxillofacial region. The lesion presents as asymptomatic in most cases until it grows to the stage of a visible swelling and moderate or severe deformity, compromising oral functions. The diagnosis is established by clinical, radiologic, and histopathologic features, and the treatment involves total resection with rare recurrences. We present the case of a 43-year-old woman with a huge, progressive, painless lesion on the left side of her face for the past 23 years. The combination of histopathologic, radiographic, and clinical features revealed a well-defined lesion that was easily enucleated from the surrounding bone. A histopathological analysis showed remarkable fibrous tissue rich in fibroblasts with spherical calcifications. The patient is under follow-up and shows considerable healing. An in-depth understanding of OF is necessary to prepare the clinicians to manage these lesions in practice.

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