Abstract

Large Intestine Histopathology of Pegylated-Interferon-Alpha Plus Ribavirin Treated Chronic Hepatitis C Patients

Highlights

  • Histological findings characteristic of inflammation as well as the presence of architectural disorders and the quantity of mucus production, the presence of ulcerations and Paneth cells as well as the numbers of lymphoid follicles in every biopsy specimen were evaluated

  • Fifteen patients underwent the same procedure after the completion of 24-week treatment course and three of them were evaluated during treatment because of diarrhea

  • All controls had no history of inflammatory bowel disease or other gastrointestinal diseases, did not receive any medication and did not report symptoms from the gastrointestinal tract

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Summary

Introduction

Histological findings characteristic of inflammation as well as the presence of architectural disorders and the quantity of mucus production, the presence of ulcerations and Paneth cells as well as the numbers of lymphoid follicles in every biopsy specimen were evaluated. Gender (male/female) Age (years) BMI (kg/m2) Inflammation (%) Architectural disorder and decrease of mucus production (%) Paneth cells (%) Lymphoid follicles

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