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Abstract
Large cell carcinoma of the lung with a rhabdoid phenotype is very rare. We report a 62-year-old male patient admitted to our hospital due to chest pains and hemoptysis. The computed tomography scan of the lungs revealed a massive consolidation of the parenchyma in the upper right lobe. The right upper lobectomy and mediastinal lymph node sampling were carried out. The microscopic appearance suggested a large cell carcinoma with a rhabdoid phenotype, with no foci of any other carcinomatous components. The tumor cells had eosinophilic cytoplasmic globules and eccentric nuclei. Immunohistochemically, vimentin was diffusely positive. The epithelial membrane antigen and neuron-specific enolase were focally positive. We expect a good outcome for this patient because the diagnostic procedure and successful operation were performed in the early stage (IA-T1aN0) of the disease.
Highlights
UDC: 616.24-006:611.018.72 to our hospital due to chest pains and hemoptysis
It is estimated that approximately 1% of these eventually develop of the right hemithorax and inhomogeneous consolidation of the paren
Received: 05.10.2010 the rhabdoid phenotype during tumor evolution [3]. It appears that the Provisionally accepted: 10.10.2010 Accepted: 13.10.2010 large cell lung carcinoma with a rhabdoid phenotype (LCLC–RP) comprises between 0.1% and 1% of all lung malignancies [4]
Summary
Large cell carcinoma of the lung with a rhabdoid phenotype is very rare. We report a 62-year-old male patient admitted. The computed tomography scan of the lungs revealed a massive. The right upper lobectomy and mediastinal lymph node sam-. Sremska Kamenica, Serbia, no foci of any other carcinomatous components. The tumor cells had eosinophilic cytoplasmic globules and eccentric. We expect a good outcome for this patient because the diagnostic procedure and suc-. Diseases of Vojvodina, Department of cessful operation were performed in the early stage (IA-T1aN0) of the disease. Correspondence to: Key worsd: Lung Neoplasms; Carcinoma, Large Cell; Neoplasms, Glandular and Epithelial; Rhabdoid Tumor. Dr Jelena Krčedinac, Institute for Pulmonary Diseases of Vojvodina, Institutski put 4, 21204 Sremska Kamenica, Serbia
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