Abstract
We describe a 50-year-old man with a history of hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu disease) who presented with chest pain, atrial fibrillation, and congestive heart failure. Echocardiography revealed a large ascending aortic aneurysm accompanied by severe aortic regurgitation and giant coronary artery aneurysms involving the right, left main, left anterior descending, and circumflex coronary arteries. Coronary angiography clearly defined multiple aneurysms involving the aorta and coronary arteries. The patient underwent complex and successful surgical repair of the aneurysms. To our knowledge, this is the first reported case of extensive cardiac involvement in a patient with this uncommon genetic disorder.
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