Large Adenomatoid Odontogenic Tumor of the Mandible: an Unusual Presentation

Abstract

Adenomatoid odontogenic tumors represent approximately 2% to 7% of all odontogenic tumors and has a striking tendency to occur in the anterior portion of the maxilla of young females. A 19-year-old man presented with a painless expansion in the anterior region of the mandible, with an 8-month evolution period. Computed tomography analysis showed a well-circumscribed radiolucent lesion with radiopaque foci involving the region from the first right lower premolar to first lower left premolar associated with an impacted canine. Histopathological examination showed proliferation of spindle-shaped cells forming solid sheets and whorled masses and rosette-like structures containing small amounts of eosinophilic material in the central space. Scant duct-like structures surrounded by cuboidal cells, foci of basophilic calcification, and deposition of large amounts of eosinophilic dentinoid matrix were present. Surgical resection with a titanium mesh placement to avoid gingival dehiscence was performed, and after a 1-year follow-up, there was no sign of recurrence.