Abstract
BackgroundIn the present study, we aimed to compare laparoscopic hepatectomy (LH) with open hepatectomy (OH) approach in patients with regional hepatolithiasis (RHL) using meta-analytical techniques. MethodsA systematic review of the literature was performed to identify studies comparing LH and OH in the management of RHL. Operative parameters, postoperative outcomes, and postoperative complications were evaluated. Meta-analysis was performed using Review Manage Version 5.0 software. ResultsNine studies matched the selection criteria, which included 719 patients (LH = 333 and OH = 386). LH was associated with shorter hospital stay (p < 0.00001), earlier oral intake (p < 0.00001), and fewer complications (p = 0.01). No significant statistical divergences were found between the LH and OH groups in terms of operative time (p = 0.48), blood loss (p = 0.07), intraoperative transfusion rate (p = 0.69), initial stone clearance rate (p = 0.33), and postoperative stone recurrence rate (p = 0.23). ConclusionLH for regional hepatolithiasis appears to be a promising treatment modality for patients with intrahepatic stones. However, large numbers of patients and prospective, randomized, controlled studies are required to lead to a more comprehensive comparison of the two procedures.
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