Laparoscopic Transperitoneal Radical Prostatectomy in Renal Transplant Recipients: A Review of Three Cases

Abstract

To report our experience with laparoscopic radical prostatectomy for the treatment of localized prostate carcinoma in 3 renal transplant recipients. We retrospectively identified all patients who had undergone laparoscopic prostatectomy for clinically localized prostate cancer between 1999 and 2006 at our institution (n = 1067). Of these patients, 3 were renal transplant recipients (dual cadaveric renal transplant, simultaneous pancreas kidney transplant, and a cadaveric renal transplant that had failed owing to chronic rejection by the time of surgery). We reviewed all available clinicopathological data. All three patients underwent successful laparoscopic radical prostatectomy without major complications. The average operative time was 237 minutes (range, 180 to 290 minutes) with a mean estimated blood loss of 425 mL (range, 75 to 1000 mL). No changes in renal graft function, measured by serum creatinine, were noted. Pathological outcomes revealed negative surgical margins with organ-confined disease in each case. All three patients tolerated the procedure well and had an average hospital stay of 3.3 days (range, 2 to 5 days). The data from our 3 patients suggest that laparoscopic radical prostatectomy is a technically feasible and safe treatment of localized prostate cancer in renal transplant recipients.