Abstract

ObjectivesThis 1:1 matched cohort study with 3-year follow-up aimed to compare the safety and efficacy of LSG with LRYGB for morbid obesity patients.MethodsFrom 2009 to 2013, patients undergoing LRYGB (n = 63) were matched with LSG (n = 63) by gender, age, and body mass index (BMI). Major complications, BMI, percentage of excess weight loss (%EWL), and obesity-related comorbidities after 6, 12, 24, and 36 months were compared.ResultsHospital stay and major complication rates were comparable, but operative time in LSG was significantly shorter (83.2 ± 23.7 vs. 108.3 ± 21.3 min). No significant differences in mean %EWL and BMI were observed at 6, 12, 24 months. At 3-year follow-up, mean %EWL in the LRYGB group was significantly higher than in the LSG group (76.5 ± 9.2% vs. 65.7 ± 10.3%) and, consequently, mean BMI was significantly lower in LRYGB (28.2 ± 1.5 vs. 30.9 ± 2.4 kg/m2). No significant differences in remission of comorbidities were observed at 1- or 3-year follow-up.ConclusionsBoth LRYGB and LSG were safe and effective bariatric procedures in this Chinese population, but LRYGB seemed to be superior to LSG in terms of mid-term weight loss.

Highlights

  • Obesity has become a worldwide public health problem in recent years

  • Physical exercise, and medication can induce some amount of weight loss, studies from Western countries have shown that bariatric surgery is the only treatment capable of providing substantial and sustainable weight loss in morbid obesity

  • A total of 126 patients were enrolled into this study, of whom 63 underwent Laparoscopic Roux-en-Y gastric bypass (LRYGB) and 63 underwent laparoscopic sleeve gastrectomy (LSG)

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Summary

Introduction

Obesity has become a worldwide public health problem in recent years. It is estimated that more than 1.9 billion people in the world are overweight or obese.[1] Many developing countries, including China, are facing an epidemic of obesity and the challenges of obesity-related diseases.[2] diet control, physical exercise, and medication can induce some amount of weight loss, studies from Western countries have shown that bariatric surgery is the only treatment capable of providing substantial and sustainable weight loss in morbid obesity. In the Orient, obese people often carry severe intra-abdominal fat accumulation with only moderately elevated body mass index (BMI). The benefit of bariatric surgery in Eastern populations is still uncertain, especially in China, where this technique has been in use for no more than 20 years

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