Abstract
Ten-year oncological experience of the University Medical Center Groningen with conventional laparotomy (C-RRRTM) and laparoscopy (L-RRRTM) is described concerning resection of residual retroperitoneal tumor masses (RRTM) in a large series of patients with advanced nonseminomatous testicular germ cell tumors (NSTGCT). 150 consecutive patients with disseminated NSTGCT required adjunctive surgery after combination chemotherapy. L-RRRTM was scheduled in 89 and C-RRRTM in 61 patients. Median residual tumor diameter was 20 mm in the L-RRRTM versus 42 mm in the C-RRRTM group (p < 0.001). Conversion rate was 15% in the L-RRRTM group. Perioperative complications occurred in 5 patients (6%) in the L-RRRTM and 7 (12%, NS) in the C-RRRTM group. Median duration of L-RRRTM was 156 minutes vs. 221 minutes for C-RRRTM (p < 0.001). 17/89 patients in the L-RRRTM group had postoperative complications versus 18/61 patients in the C-RRRTM group (NS). Median postoperative stay in the L-RRRTM group was 2 vs. 6 days in the C-RRRTM group (p < 0.001). During a median follow-up of 79 months, 27 patients had recurrences: 8 (9%) in the L-RRRTM group and 19 (31%) in the C-RRRTM group (p < 0.001). Laparoscopic resection of RRTM for advanced NSTGCT is feasible and an oncologically safe option in appropriately selected patients.
Highlights
The current study aimed to describe the 10-year experience of the Comprehensive Cancer Center of the University Medical Center Groningen UMCG with conventional resection of retroperitoneal tumor masses (RRTM) (C-retroperitoneal tumor masses (RRRTM)) and laparoscopic resection of RRTM (L-RRRTM) in a consecutive series of patients and compared first the intra and postoperative morbidity data of L-RRRTM group with the C-RRRTM group and secondly focused on long-term oncologic outcome of both surgical procedures
Patients with good prognoses according to the International Germ Cell Cancer Collaborative Group (IGCCCG), were more likely to undergo L-RRRTM than C-RRRTM (81% vs. 29%; p < 0.001)
This is currently the largest series published in literature with respect to laparoscopic resection of RRTM after cisplatin based combination chemotherapy for metastatic nonseminomatous testicular germ cell tumors (NSTGCT)
Summary
Ten-year oncological experience of the University Medical Center Groningen with conventional laparotomy (C-RRRTM) and laparoscopy (L-RRRTM) is described concerning resection of residual retroperitoneal tumor masses (RRTM) in a large series of patients with advanced nonseminomatous testicular germ cell tumors (NSTGCT). For the laparoscopic resection of RRTM to be considered a safe alternative oncologic procedure compared to conventional open surgery in patients with advanced NSTGCT, long-term follow up assessments in a larger cohort are required. The current study aimed to describe the 10-year experience of the Comprehensive Cancer Center of the University Medical Center Groningen UMCG with conventional resection of RRTM (C-RRRTM) and laparoscopic resection of RRTM (L-RRRTM) in a consecutive series of patients and compared first the intra and postoperative morbidity data of L-RRRTM group with the C-RRRTM group and secondly focused on long-term oncologic outcome of both surgical procedures. Were the oncological and technical boundaries for laparoscopic management in the field of adjunctive surgery after cisplatin combination chemotherapy in patients with testicular cancer defined
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
